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FEATURE

Better Understanding of Cancer Metastasis Suggests Better Treatment Approaches
By Beverly A. Caley

Evidence presented on Saturday at SABCS emphasized that breast cancer metastasis is even more complicated than previously thought. However, researchers are making progress ... [MORE]

DAILY BLOGS

	>> Debu Tripathy, MD EDITOR-IN-CHIEF, CURE Today’s sessions at San Antonio focused on diagnosis and detection—obviously an important topic since advances in this area with earlier detection have been one of the key reasons that more women are cured after a diagnosis of breast cancer. Along with advances in screening has come the fact ... [MORE]
	>> Susan McClure VICE PRESIDENT & PUBLISHER, CURE This morning, I was fortunate enough to finally meet “Bear,” the male breast cancer survivor I told you about yesterday. He was exactly as described … tall, kind, and strong. I told him that he had touched so many on my staff, and that even though we hadn’t met, I felt compelled to share a small part of his story... [MORE]
	>> Joan Venticinque ADVOCATE & GUEST BLOGGER Day three of the SABCS brought many presentations on HER2 research. Scientists are looking at the many pathways that target the cell signaling in tumors that overexpress HER2. I think our HER2 sisters can feel like the future will bring many therapies for them. During the mentoring session Thursday night, one of the doctors made the comment that we could have a great drinking game if... [MORE]

BRIEFS

• Zometa May Have Direct Effect on Breast Tumors:Adding Zometa (zoledronic acid) to chemotherapy before surgery led breast tumors to shrink by an additional third, according to a subset analysis of the AZURE trial. This is the first patient-related evidence that Zometa, a bisphosphonate drug used to treat cancer-related bone loss, has an anti-tumor effect... [MORE]

• Breast Density Reduction Predicts Tamoxifen's Preventive Effect: Initially published in 2002, IBIS-1 was one of the first trials examining tamoxifen in breast cancer prevention, following more than 7000 patients over eight years. Tamoxifen, a hormonal agent that blocks the effects of estrogen, has been used for decades for the treatment and prevention of hormone-positive breast cancer. However, many women at high risk do not take the drug... [MORE]

• Oncotype DX Predicts Recurrence With Aromatase Inhibitor Treatment: Researchers presenting the TransATAC study at SABCS Saturday morning showed results for the first time that Oncotype DX, a test to predict recurrence, could be used in women who had taken aromatase inhibitors. It also marked the largest study of the genetic assay to date... [MORE]

• Studies Offer Insight Into Breast Cancer Risk and Mortality for Former HRT Users: There’s good news for women who took hormone replacement therapy: If you stopped taking HRT, your chance of getting cancer drops dramatically, and if you do get cancer, you’re more likely to survive... [MORE]

ADVOCACY STORY

A Few Good Men: Educating the Public About Male Breast Cancer
Robert Kaitz, 49, had the lump under his left nipple for more than a year before pointing it out to his general practitioner. "I had cysts on my back and just thought it was another cyst," Katz says. But it wasn't a cyst... [MORE]